一項耗資 3,800 萬美元的新研究旨在測試常見藥物是否能延緩衰老並促進健康。

New $38 million study tests if common drugs can extend healthy aging

一項名為VITAL-H,耗資3800萬美元的開創性研究,正在挑戰我們對於變老(ㄅㄧㄢˋㄌㄠˇ)的看法。

A groundbreaking $38 million study called VITAL-H is challenging how we approach getting older.

eventVITAL-H
conceptaging

這項臨床試驗由德州大學聖安東尼奧分校健康科學中心的Barshop研究所領導,旨在將醫學的重點從疾病出現後的治療,轉向更前瞻性的作法。

Led by the Barshop Institute at UT Health San Antonio, this clinical trial aims to move medicine beyond just treating diseases after they appear.

orgUniversity of Texas Health Science Center at San Antonio
orgBarshop Institute

相反地,該研究的目標是透過測試現有且經FDA批准的藥物是否能減緩生物學上的老化,來主動改善「健康壽命」(我們維持健康狀態生活的年數)。

Instead, the goal is to proactively improve 'healthspan'—the number of years we live in good health—by testing if existing, FDA-approved medications can slow down biological aging.

orgFood and Drug Administration
concepthealthspan

在美國衛生高級研究計畫局(ARPA-H)的資助下,該研究將追蹤726名60至65歲的成年人。

Funded by the Advanced Research Projects Agency for Health (ARPA-H), the study will follow 726 adults between 60 and 65.

orgARPA-H

參與者將接受三種藥物測試:雷帕黴素(Rapamycin)、達格列淨(Dapagliflozin)和司美格魯肽(Semaglutide)。

Participants will be tested with three drugs: Rapamycin, Dapagliflozin, and Semaglutide.

techRapamycin
techDapagliflozin
techSemaglutide

其最終的抱負是縮小壽命與健康壽命之間的差距,確保我們在活得更久的同時,也能保持更獨立且充滿活力的狀態。

The ultimate ambition is to narrow the gap between our lifespan and our healthspan, ensuring that as we live longer, we also stay more independent and vibrant.

concepthealthspan
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End of article

You read 6 focus sentences.

Challenge Mode

Comprehension Questions

VITAL-H試驗的主要目標是什麼?

Correct Choice

確定現有藥物是否能延長健康壽命並延緩與年齡相關的機能衰退。

哪一個機構為這項研究提供資金?

Correct Choice

美國衛生高級研究計畫局(ARPA-H)。

預計有多少參與者會加入這項研究?

Correct Choice

726名成年人。

「健康壽命」一詞是指什麼?

Correct Choice

一生中處於健康狀態的時期。

為什麼VITAL-H研究被認為是方法論上的轉變?

Correct Choice

它將長壽研究從動物模型轉向人體臨床試驗。

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