New Patent Granted for Prostate Cancer Drug Masitinib

治療前列腺癌藥物 Masitinib 獲頒新專利

更新於: 2026年6月18日 上午02:01

A significant breakthrough in oncology has emerged as AB Science SA secured a U.S. patent for its lead compound, masitinib, targeting metastatic castrate-resistant prostate cancer (mCRPC).

腫瘤學領域出現重大突破,AB Science SA 公司針對其領先化合物「馬賽替尼」(masitinib) 取得了美國專利,該藥物旨在治療轉移性去勢抗性前列腺癌 (mCRPC)。

nounbreakthrough
nounoncology
verbsecure
nounpatent
nounmasitinib
adjectivemetastatic

This patent, valid until 2042, marks a pivotal moment for a field that has seen no new combination therapies for nearly two decades.

此項專利有效期限至 2042 年,對於已近二十年未見新式聯合療法的領域而言,標誌著一個關鍵時刻。

nounpatent
adjectivepivotal

Masitinib works as a protein kinase inhibitor, intended to be used alongside docetaxel.

馬賽替尼是一種蛋白激酶抑制劑,預計與多西他賽 (docetaxel) 合併使用。

nouninhibitor

What sets this treatment apart is its commitment to precision medicine.

此療法與眾不同之處在於對精準醫療的承諾。

nounprecision

Clinical data from the Phase 3 AB12003 study showed a 21% reduction in disease progression risk for patients with ALP levels at or below 250 IU/L.

第三期臨床試驗 AB12003 的數據顯示,對於 ALP 數值不高於 250 IU/L 的患者,其疾病惡化風險降低了 21%。

nounreduction

The long-term patent protection provides the stability needed for large-scale clinical trials, signaling a hopeful shift toward personalized, biomarker-driven cancer care.

長期的專利保護提供了進行大規模臨床試驗所需的穩定性,標誌著醫療界正朝向個人化、以生物標記為導向的癌症護理邁出充滿希望的一步。

nounpatent
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文章閱讀結束

你閱讀了 6 句重點內容。

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閱讀理解

What is the primary function of masitinib in the context of mCRPC treatment?

正確答案

It is a protein kinase inhibitor used as a combination therapy.

Why is the use of the biomarker alkaline phosphatase (ALP) significant?

正確答案

It helps identify patients who will most likely benefit from the therapy.

How long does the newly granted U.S. patent protect masitinib?

正確答案

Until May 2042.

What did the Phase 3 AB12003 study demonstrate regarding patient outcomes?

正確答案

A 21% reduction in the risk of disease progression for specific patients.

What is the goal of the upcoming confirmatory Phase 3 trial, AB22007?

正確答案

To definitively confirm the safety and efficacy of the masitinib-docetaxel combination.

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