Researchers discover potential treatment to reverse lung scarring
研究人員發現逆轉肺部纖維化的潛在治療方法
For decades, pulmonary fibrosis has been considered an irreversible condition.
數十年來,肺纖維化一直被認為是一種不可逆轉的疾病。
While current medications like nintedanib and pirfenidone help slow down the disease, they cannot fix the damage that has already occurred.
儘管目前的藥物如 nintedanib 和 pirfenidone 有助於減緩疾病進程,但它們無法修復已經造成的損傷。
By targeting proteins like interleukin-11 (IL-11) or inhibiting the YAP/TAZ proteins in immune cells, scientists have successfully stimulated tissue regeneration in laboratory models.
透過標靶白血球介素-11(IL-11)等蛋白質,或抑制免疫細胞中的 YAP/TAZ 蛋白質,科學家已成功在實驗室模型中刺激了組織再生。
Nevertheless, the discovery that fibrosis is not biologically fixed represents a monumental shift in pulmonary medicine.
儘管如此,發現纖維化並非生物學上的定局,這代表了肺部醫學的重大轉變。
