最新研究發現腸道細菌與肌萎縮性脊髓側索硬化症及失智症有關
New study links gut bacteria to ALS and dementia
一項近期發表在《細胞報告》(ㄒㄧˋㄅㄠㄅㄠˋㄍㄠˋ)期刊的研究，揭示了我們的消化系統與大腦健康之間具有開創性的關聯。
A recent study published in Cell Reports has revealed a groundbreaking link between our digestive systems and brain health.
凱斯西儲大學的研究人員發現，有害的腸道細菌會產生一種變異形式的肝糖，這類肝糖會成為誘發肌萎縮性脊髓側索硬化症 (ALS) 以及額顳葉失智症 (FTD) 等疾病的發炎觸發因子。
Researchers at Case Western Reserve University discovered that harmful gut bacteria produce a modified form of glycogen that acts as an inflammatory trigger for diseases like Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD).
多年來，科學家們一直難以解釋為何帶有相同 C9orf72 基因突變的人，其健康結果卻大不相同。
For years, scientists struggled to explain why individuals with the same genetic C9orf72 mutation faced different health outcomes.
這項研究支持了日益受到重視的「腸腦軸線」(ㄔㄤˊㄋㄠˇㄓㄡˊㄒㄧㄢˋ)理論，將我們對神經退化性疾病的觀點，從單純的遺傳問題，轉向為可能透過微生物群進行管理的疾病。
This research supports the growing theory of the Gut-Brain Axis, shifting our view of neurodegenerative diseases from purely genetic concerns to conditions potentially manageable through the microbiome.
