科學家培育出能鎖定並對抗癌症的細菌
Scientists Create Bacteria That Target and Fight Cancer
科學家正運用合成生物學徹底改變癌症治療，將細菌轉化為活的藥物工廠。
Scientists are revolutionizing cancer treatment using [synthetic biology|noun], transforming bacteria into living drug factories.
傳統治療如化學治療往往會損害健康組織，但經過改造的細菌，例如一種經過改良的益生菌大腸桿菌，能夠直接進入實體腫瘤中氧氣稀薄的核心。
Traditional treatments like chemotherapy often harm healthy tissue, but engineered bacteria, such as a modified version of the probiotic E. coli, can navigate directly to the low-oxygen cores of solid tumors.
一旦到達，這些細菌便化身為專業的遞送載體，僅在腫瘤部位釋放抗癌藥物。
Once they arrive, these bacteria act as specialized delivery vehicles, releasing anticancer drugs exclusively at the site.
這種精準標靶不僅將副作用降至最低，同時還能警示免疫系統攻擊隱藏的癌細胞。
This precise targeting minimizes side effects while simultaneously alerting the [immune system|noun] to attack hidden cancer cells.
2026年3月的一項著名研究顯示，此方法能在小鼠模型中有效遞送抗癌藥物羅米地辛。
A notable study from March 2026 demonstrated that this method could deliver the anticancer drug [Romidepsin|noun] effectively in mouse models.
儘管此概念可追溯至19世紀威廉·科利醫生的觀察，但現代科技已將其精煉成一種安全且受控的方法。
While the concept traces its roots back to the 19th-century observations of Dr.
研究人員目前正致力於解決重大挑戰，包括確保細菌不會擴散至健康器官，以及通過嚴格的安全法規。
William B.
雖然仍處於研究初期，但這些微小的微生物助手代表了抗癌事業的未來願景，有望成為傳統療法之外，更強效且毒性更低的替代選擇。
Coley, modern technology has refined it into a safe, controlled approach.
