慶祝誘導性多功能幹細胞研究 20 週年
Celebrating 20 years of induced pluripotent stem cell research
2026年是一個重要的里程碑：誘導性多能幹細胞發現20週年。
The year 2026 marks a major milestone: the 20th anniversary of the discovery of induced pluripotent stem cells (iPSCs).
2006年，研究人員山中伸彌和高橋和利透過將成體細胞重編程為類幹細胞狀態，徹底改變了科學界。
In 2006, researchers Shinya Yamanaka and Kazutoshi Takahashi transformed science by reprogramming adult cells into a stem cell-like state.
藉由使用特定的因子——Oct4、Sox2、Klf4和c-Myc——他們證明了細胞發育可以是雙向的。
By using specific factors—Oct4, Sox2, Klf4, and c-Myc—they proved that cellular development could be a two-way street.
科學家現在可以創造「疾病模型」(disease-in-a-dish)，從而進行更安全的藥物測試，並對帕金森氏症等疾病進行更深入的研究。
Scientists can now create disease-in-a-dish models, allowing for safer drug testing and deeper study into conditions like Parkinson’s disease.
展望未來，將iPSC技術與基因編輯和人工智慧相結合，預計將進一步徹底改變醫學。
As we look forward, the integration of iPSC technology with gene editing and artificial intelligence promises to revolutionize medicine further.
