最新結核病疫苗試驗結果顯示成效不一
Latest Tuberculosis Vaccine Trial Results Show Mixed Success
一個多世紀以來,卡介苗(BCG)一直是對抗結核病(TB)的唯一工具。
For over a century, the BCG vaccine has been the only tool against tuberculosis (TB).
2026年4月在印度進行的評估VPM1002和Immuvac的第三期臨床試驗突顯了疫苗研究中複雜且參差不齊的現狀。
Recent April 2026 Phase 3 trials in India evaluating VPM1002 and Immuvac highlight a complex, mixed landscape in vaccine research.
兩種候選疫苗都未能成功預防常見的肺結核。
Neither candidate succeeded in preventing common pulmonary TB.
然而,VPM1002在對抗致命的肺外結核方面達到了顯著的50.4%防護效力,並且在6至14歲的兒童群體中展現了約65%的效力。
However, VPM1002 achieved a notable 50.4% efficacy against deadly extrapulmonary TB, and showed ~65% efficacy in children aged 6–14.
與此同時,M72/AS01E疫苗依然是該領域的領先者。
Meanwhile, the M72/AS01E vaccine remains the field's frontrunner.
研究人員正在邁向精準免疫,而非追求單一的「聖杯」疫苗。
Instead of seeking a single 'holy grail' vaccine, researchers are moving toward precision immunization.
