New Research Examines the Link Between HIV and Cognitive Aging
New Research Examines the Link Between HIV and Cognitive Aging
Thanks to modern antiretroviral therapy (ART), HIV has evolved from a fatal diagnosis into a manageable chronic condition.
As a result, many people living with HIV (PLWH) are reaching older ages.
Today, about half of the HIV-positive population in the U.S. is over 50.
With this success comes a new clinical focus: cognitive aging.
While severe HIV-associated dementia is now rare, milder issues with memory, attention, and executive function—collectively known as HIV-Associated Neurocognitive Disorder (HAND)—persist in many individuals.
Scientists are currently investigating the "acceleration" hypothesis, which suggests that HIV might cause the brain to age faster.
This process is likely driven by a mix of factors, including persistent low-level neuroinflammation, the historical impact of the virus on the nervous system, and other health comorbidities like cardiovascular disease.
Moving forward, the goal is to incorporate regular cognitive screenings into standard HIV treatment, ensuring that as patients live longer, they also maintain the best possible quality of life and brain health.
